Ingredient profile: gymnema
Gymnema in Payarmin: At Most 25 mg Per 1 ml Serving
Gymnema sylvestre in Payarmin is a leaf extract listed eighth in the 200 mg blend, so one 1 ml serving holds at most 25 mg. Small trials used 200 to 400 mg a day of a standardized extract and saw a small fall in fasting glucose. No trial has tested Payarmin itself.
Written by the Payarmin label deskUpdated
The label line
What is gymnema in Payarmin?
Gymnema sylvestre in Payarmin is a leaf extract, listed as “Gymnema Leaf Extract” and ranked eighth of the 22 blend ingredients.
The label prints no species and no amount. The sales page names gymnema as one of six headline ingredients (Payarmin sales page).
Gymnema is a leaf used in Ayurvedic tradition. In research it is known for blunting the taste of sweetness and for small glucose studies (Gymnema monograph per Drugs.com).
The blend runs from most to least by weight. Gymnema is eighth, behind maca, grape seed, guarana, African mango, eleuthero, astragalus and green tea.
That rank tells you something real. Seven ingredients must each weigh at least as much as gymnema, so gymnema cannot be a large share of the 200 mg (21 CFR 101.36 (eCFR)).
The label spells the ingredient without the species. We write gymnema sylvestre because that is the plant the research covers, and we say when the label is silent.
The math
How much gymnema fits in one serving?
A 1 ml serving of Payarmin holds at most 25 mg of gymnema. That is the 200 mg blend divided by gymnema’s place, 8, and the real amount is probably lower.
An even split of the 22 ingredients would give about 9 mg. Both figures sit under the 200 to 400 mg a day that trials used (Gymnema monograph per Drugs.com).
The label never says how many mL a dropper holds, so two droppers a day may or may not double these numbers.
| Figure | Amount | Share of the 200 mg trial dose |
|---|---|---|
| Even split of the blend | About 9 mg | About 4.5% |
| Ceiling for place 8 | At most 25 mg | At most 12.5% |
| Whole bottle at the ceiling (30 servings) | At most 750 mg | Under 4 days of the low trial dose |
| Lowest trial dose | 200 mg a day | 100% |
Ceilings are arithmetic from the label order, not measured amounts.
The research
What do gymnema studies show?
Gymnema studies show a small effect. A 2021 meta-analysis of 10 small studies found a statistically significant but clinically small drop in fasting glucose (Gymnema monograph per Drugs.com).
Most diabetes trials gave 200 to 400 mg a day of an extract standardized to 25% gymnemic acids. Others gave 500 to 1,000 mg a day of leaf extract.
Robust clinical trials are still lacking. NCCIH says no herbal supplement has reliable evidence for controlling diabetes (Diabetes and Dietary Supplements per NCCIH).
200 to 400 mg
A day, of a 25% gymnemic acid extract, in the typical diabetes study.
Small
A fasting-glucose dip across 10 small studies, with little clinical weight.
No product trial
Nothing tests gymnema at 25 mg or less inside a 22-ingredient blend.
Sweet taste
Why is gymnema linked to sweet taste?
Gymnema is best known for reducing the taste of sweetness, an effect that is reversible (Gymnema monograph per Drugs.com).
Payarmin also holds stevia extract and xylitol as sweeteners, so the drops are built to taste sweet.
We found no source that says what a gymnema amount of 25 mg or less does to taste in a liquid like this.
The sweet-taste effect explains why gymnema shows up in sugar-craving products. It is a taste effect, not a proof of a change in blood sugar.
Whatever you notice on your tongue, judge the drops by your lab results, not by taste.
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View packsSales page claim
What does the sales page say gymnema does?
The sales page says gymnema “helps regenerate the pancreatic cells that produce insulin”. It names no study, no amount and no test of the product (Payarmin sales page).
We found no human evidence in our sources for rebuilding pancreatic cells. The small trials measured fasting glucose, not cell regrowth (Gymnema monograph per Drugs.com).
A health claim needs competent and reliable evidence, usually human trials of the same product and dose (Health Products Compliance Guidance per FTC).
| Source | What it says |
|---|---|
| Sales page | Quoted claim about pancreatic cells. No amount. |
| Label | Eighth of 22, no amount, so at most 25 mg per 1 ml. |
| Research | A small fasting-glucose drop at 200 to 400 mg a day. |
The other five named ingredients are on the benefits page.
Safety
Does gymnema mix well with diabetes medicine?
It may not. Gymnema has a glucose effect, and the ADA warns that some supplements can cause low blood sugar when taken with diabetes medicines (Vitamins & Supplements per ADA).
A reversible liver-injury case report also exists for gymnema (Gymnema monograph per Drugs.com). It is a single report, not a measured rate.
Keep taking every prescribed medicine and dose. Do not stop or change one because of a supplement.
Anyone on insulin, a sulfonylurea or another glucose drug. The label also asks pregnant or nursing mothers, anyone under 18 and anyone with a known medical condition to consult a physician.
Signs of a low are shakiness, sweating, hunger, dizziness, confusion and a fast heartbeat (Low Blood Glucose per NIDDK).
Label profile
Where does gymnema sit among the 23 label lines?
Gymnema is line 8 of the 22 blend names, after chromium. The tables below set it beside the research.
Next in the series are African mango and Panax ginseng, which sit in places 4 and 12.
| Printed name | Gymnema Leaf Extract |
|---|---|
| Kind of ingredient | Gymnema sylvestre leaf (the label prints only 'Gymnema Leaf Extract') |
| Where it sits | 8 of 22 in the 200 mg proprietary blend |
| Content in 1 ml | No printed amount; ranked 8 of 22 in the 200 mg blend, which caps it near 25 mg per 1 ml |
| Dose in studies | 200-400 mg a day of a 25% gymnemic acid extract |
| How strong the evidence is | Small trials; a small fasting-glucose drop |
| Usual marketing or folk use | Ayurvedic leaf |
| Chief caution | May add to diabetes medicines; dulls sweet taste. |
FAQ
Questions people raise about gymnema?
One to start with: How much gymnema is in Payarmin? Plus 5 more answered below.
Each answer gives the plain reply first, then the reasoning and a citation where available.
How much gymnema is in Payarmin?
The label does not say. Gymnema is eighth in a 200 mg blend of 22, so one 1 ml serving holds at most 25 mg and probably about 9 mg or less on an even split (21 CFR 101.36 (eCFR)). Studies used 200 to 400 mg a day (Gymnema monograph per Drugs.com).
What does gymnema do to sweet taste?
Gymnema reduces the taste of sweetness, and the effect is reversible (Gymnema monograph per Drugs.com). That is its best-known action. We found no source on how much gymnema in a liquid with stevia and xylitol would change taste, so we make no claim.
Is gymnema safe with diabetes medicine?
Ask first. Gymnema has a small glucose effect, and the ADA warns that some supplements cause lows with diabetes medicines (Vitamins & Supplements per ADA). A reversible liver-injury case report also exists (Gymnema monograph per Drugs.com). Keep taking your prescribed medicine and tell your doctor.
Can gymnema cause low blood sugar?
It may add to the effect of diabetes medicines, and lows are the risk the ADA flags for supplements taken with them (Vitamins & Supplements per ADA). Trials show a small glucose dip. Signs of a low are shaking, sweating, hunger and confusion (Low Blood Glucose per NIDDK).
What dose of gymnema did studies use?
Most diabetes studies used 200 to 400 mg a day of an extract standardized to 25% gymnemic acids. Others used 500 to 1,000 mg a day of leaf extract (Gymnema monograph per Drugs.com). Payarmin holds at most 25 mg in a 1 ml serving.
Who should avoid gymnema?
Anyone on diabetes drugs should ask a doctor first, and so should anyone with liver trouble, given the case report (Gymnema monograph per Drugs.com). The label asks pregnant or nursing mothers, children under 18 and people with a known condition to consult a physician.
Who wrote this
Who wrote and reviewed this Payarmin guide?
The Payarmin label desk drafted these pages from the bottle label, the order page and public research links.
The clinician who reviews these pages is named in the box below when that review exists.
Every page starts at the printed bottle label, quotes the order page, and links outside research.
Page updated . How we work: editorial standards and how reviews are checked. This site belongs to an authorized Payarmin shop. It is separate from the maker and from the distributor named on the label. Orders placed through our links pay the shop a commission.
Keep reading
Where to go next
Good next stops are ingredients, side effects, panax ginseng (aerial).
All three use the same label facts and cite their research.
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